Developing Next Generation Technologies and Beyond; Quick-Med Technologies

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Matrix Metalloproteinases (MMPs)

Matrix Metalloproteinases, or “MMPs”, are naturally occurring compounds in skin tissue. External or internal stimuli can trigger an overproduction of certain MMPs, which can produce chemical reactions within skin cells that induce adverse outcomes such as blistering, inflammation or accelerated collagen degradation. External triggers include prolonged sun exposure as well as chemical burns from warfare agents such as mustard gas. Internal triggers include natural aging in which declining estrogen levels cause increased levels of MMPs and leads to accelerated skin wrinkling. There are natural or synthetic compounds that safely inhibit MMP overproduction in the skin (MMP-inhibitors, or “MMPIs”). These MMPIs can be topically applied to mitigate the affects of triggering mechanisms. The bioscience of MMPI research includes the identification of safe compounds that individually or in combination yield a specific beneficial outcome. MultiStat™ represents the Company’s family of patented compounds and techniques relating to MMP inhibition. MultiStat™’s array of uses has been documented in a series of clinical findings by Quick-Med Technologies’ scientists, who are consultants, employees, or third party scientific laboratories, or published by other academic researchers.

What is MultiStat™?

MultiStat™ is part of MMPI-related technologies consisting of over 10 patented compounds, patented formulae for developing other compounds, numerous use or method patents and other intellectual property or trade secrets involving the use of MMP inhibition techniques in skin therapy.

MultiStat™’s wide array of uses has been documented in a series of clinical findings that include:

Significant reducing corneal ulcerations and perforations;
Reducing rabbit scarring and vascularization after sulfur mustard injury;
Reducing inflammation in a mouse skin model of psoriasis;
Preventing death of mice after a lethal dose of endotoxin;
Counteracting the effects of photo or natural skin aging;
Rapidly reducing the number and depth of facial wrinkles in male and female subjects.

Target Markets :

Pharmaceutical

Cosmetics